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目的利用封闭式缝合的羊膜与角膜之间的空隙注入自血,留置形成血膜治疗眼表疾病。方法在手术显微镜下机械清除眼表病变组织后,羊膜遮盖角膜、球结膜,环型连续封闭式缝合在球结膜上,取自血注入羊膜与角膜之间,使之形成血膜。结果治疗单疱角膜炎17例、大疱性角膜炎9例、角膜瘘2例、重度电光性眼炎3例、酸性伤16例、碱性伤11例、热烧伤13例、非化脓性角膜溃疡17例、角膜移植创口溃疡4例,共计92例。术后明显刺激症状改善,术前难以忍受的疼痛全部消失。羊膜拆除后角膜上皮染色阴性,眼表面稳定达到79例占86％(79/92)。因本法应用导致病情加重者为零。结论本法应用羊膜不是移植而是作为生物膜起到衬里作用包敷自血形成血膜,对眼表疾病的刺激症状及疼痛有明显镇痛作用。对眼表的多种疾病创面修复有显著效果。是基层医院临床应用有效方法。
Objective The use of closed suture amniotic membrane and corneal interstitial injection of blood, indwelling blood film formation of ocular surface disease. Methods After surgical removal of ocular surface lesions by surgical microscope, the amniotic membrane covered the cornea, conjunctiva and ring in a continuous closed suture on the conjunctiva. Blood was injected into the amniotic membrane between the cornea to form a blood film. Results 17 cases were treated with herpes simplex keratitis, 9 cases with bullous keratitis, 2 cases with corneal fistula, 3 cases with severe electro-optic ophthalmia, 16 cases with acid injury, 11 cases with alkaline injury, 13 cases with thermal burn, non-suppurative cornea 17 cases of ulcer, 4 cases of corneal wounds and ulcers, a total of 92 cases. Significantly improved postoperative irritation, unbearable pain before surgery all disappeared. After amniotic membrane removal corneal epithelial staining was negative, the eye surface stability reached 79 cases accounted for 86% (79/92). Due to the application of this Law lead to aggravating those who are zero. Conclusion The application of amniotic membrane in this method is not transplanting but as a biofilm which plays the role of lining to form a blood film from blood and has obvious analgesic effect on irritation and pain of ocular surface diseases. A variety of diseases on the ocular surface repair wounds have a significant effect. Is an effective method of clinical application of primary hospital.