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目的 :观察利多卡因治疗新生儿惊厥的疗效。方法 :选择 36例新生儿惊厥患儿 ,随机分为两组 :治疗组对照组各18例 ,治疗组首次用利多卡因 2mg/kg静脉注射 ,2 0~ 30min后如无效 ,可重复上述剂量 ,缓解后用 4~ 6mg/kg·h维持。对照组用鲁米那 ,首次 10mg/kg以 0 .5mg/kg·min的速度静脉推注 ,12h后改用维持量 5mg/kg静脉给药。结果 :治疗组止惊时间较对照组明显缩短 ;治疗组止惊时间 6 .7± 1.1min ,对照组 15 .2± 2 .4min。结论 :利多卡因治疗新生儿惊厥起效快 ,毒副作用少。
Objective: To observe the efficacy of lidocaine in the treatment of neonatal convulsion. Methods: Thirty-six neonates with convulsions were selected and randomly divided into two groups: control group, 18 cases each, intravenous injection of lidocaine 2 mg / kg for the first time and no effect after 20-30 minutes, , Ease with 4 ~ 6mg / kg · h to maintain. Control group with luminal, the first 10mg / kg at 0. 5mg / kg · min speed intravenous injection, 12h after the switch to the maintenance dose of 5mg / kg intravenous administration. Results: The treatment group was significantly shorter than the control group; the treatment group only shock time 6.7 ± 1.1min, the control group 15.2 ± 2. 4min. Conclusion: Lidocaine treatment of neonatal convulsions rapid onset, fewer side effects.