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目的:分析老年早期无症状动脉粥样硬化的危险因素。方法:对204名老年人进行脉搏波传导速度的测量并以1 400 cm/s为界,将所有对象分为对照组与无症状动脉粥样硬化组,比较各危险因素在两组中的情况。结果:无症状动脉粥样硬化组的空腹血糖、超敏C-反应蛋白、尿酸、血压和体重指数水平显著高于对照组(P<0.05)。Logistic回归显示血糖、超敏C-反应蛋白和收缩压是老年人无症状动脉粥样硬化的独立危险因子。结论:血糖、超敏C-反应蛋白和收缩压在早期动脉粥样硬化的发展过程中起了促进作用,加强对这些影响因素的早期预防和干预有望减少心血管事件的发生。
Objective: To analyze the risk factors of asymptomatic atherosclerosis in the elderly. Methods: The pulse wave velocity was measured in 204 senile people and all the subjects were divided into control group and asymptomatic atherosclerosis group by 1 400 cm / s, and the comparison of risk factors between the two groups . Results: Fasting plasma glucose, high sensitivity C-reactive protein, uric acid, blood pressure and body mass index in asymptomatic atherosclerosis group were significantly higher than those in control group (P <0.05). Logistic regression showed that blood glucose, high-sensitivity C-reactive protein and systolic blood pressure were independent risk factors for asymptomatic atherosclerosis in the elderly. CONCLUSIONS: Blood glucose, high-sensitivity C-reactive protein and systolic blood pressure play a role in the development of early atherosclerosis. It is expected that early prevention and intervention of these factors may reduce the occurrence of cardiovascular events.