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目的 探讨吸烟与代谢综合征的关系。方法 应用整体抽样横断面调查方法 ,完成重庆地区 371 7例自然人群问卷调查及口服 75 g葡萄糖耐量试验 ,检测空腹血糖、血脂、血浆胰岛素及糖负荷 2h后血糖 ,测量空腹状态血压、腰围、体重、身高。结果 (1 ) 887例正常人中 ,吸烟组体重指数 (BMI)、腰臀比 (WHR)、体重、腰围、甘油三酯 (TG)及低密度脂蛋白胆固醇 (LDL C)高于非吸烟组 ,高密度脂蛋白胆固醇 (HDL C)低于非吸烟组。 (2 ) 3379例资料完整自然人群按年龄分层后 ,4 0岁以下人群吸烟组糖尿病 (DM)、糖耐量减低 (IGT)、空腹血糖减损 (IFG)、高血压、血脂紊乱、超重 /肥胖及中心性肥胖的患病率高于非吸烟组。 4 0～ 6 0岁年龄层吸烟组超重 /肥胖及中心性肥胖、高TG、低HDL C的患病率高于非吸烟组 ,6 0岁以上年龄层吸烟组代谢综合征患病率高于非吸烟组。结论 吸烟与代谢综合征有关 ,是其发生、发展的重要环境因素之一。
Objective To explore the relationship between smoking and metabolic syndrome. Methods A total of 371 subjects in Chongqing area were surveyed by questionnaire and oral glucose tolerance test (75 g). The blood glucose, fasting blood glucose, plasma insulin and glucose in blood were measured 2h later. Blood pressure, waist circumference, body weight ,height. Results (1) Among 887 normal subjects, body mass index (BMI), WHR, body weight, waist circumference, triglyceride (TG) and low density lipoprotein cholesterol (LDL C) , High-density lipoprotein cholesterol (HDL C) was lower than non-smoking group. (2) The DM group, IGT, IFG, hypertension, dyslipidemia, overweight / obesity group were significantly higher in smokers under 40 years old than in 3379 cases with data complete and natural population stratified by age And the prevalence of central obesity is higher than non-smoking group. The prevalence rates of overweight / obesity and central obesity, high TG and low HDL C in 40-60 age group were higher than those in non-smoking group, while the prevalence of metabolic syndrome in over 60 age group was higher than that of non-smoking group Non-smoking group. Conclusion Smoking is related to metabolic syndrome, which is one of the important environmental factors of its occurrence and development.