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[目的]探讨二氯化锶(89SrCl2)联合云克(99Tc-MDP)治疗乳腺癌骨转移瘤的疗效。[方法]87例乳腺癌骨转移患者分为A、B组,A组45例患者采用单一89SrCl2治疗,B组42例患者采用89SrCl2联合99Tc-MDP治疗。[结果]A组患者治疗总有效率为82.2%,B组患者治疗有效率为95.2%,B组有效率高于A组(χ2=4.381,P<0.05)。两组白细胞下降及血小板减少均为一过性。[结论]89SrCl2联合99Tc-MDP治疗乳腺癌骨转移瘤疗效肯定,不良反应轻。
[Objective] To investigate the therapeutic effect of strontium chloride (89SrCl2) and Yunke (99Tc-MDP) on breast cancer patients with bone metastases. [Method] 87 patients with breast cancer with bone metastases were divided into group A and group B. 45 patients in group A were treated with 89SrCl2 alone and 42 patients in group B were treated with 89SrCl2 and 99Tc-MDP. [Results] The total effective rate of treatment in group A was 82.2%. The effective rate of treatment in group B was 95.2%. The effective rate in group B was higher than that in group A (χ2 = 4.381, P <0.05). Two groups of leukopenia and thrombocytopenia were transient. [Conclusion] 89SrCl2 combined with 99Tc-MDP is effective in treatment of breast cancer with bone metastases and has mild adverse reactions.