论文部分内容阅读
目的观察臭氧辅治霉菌性阴道炎对患者血清白细胞介素8(IL-8)、白细胞介素10(IL-10)及肿瘤坏死因子-α(TNF-α)水平的影响。方法将212例霉菌性阴道炎患者随机分为观察组和对照组各106例。对照组患者给予达克宁栓和伊曲康唑胶囊治疗,观察组在对照组基础上联合臭氧治疗。对比2组治疗前后血清IL-8、IL-10及TNF-α的水平。结果治疗后2组患者的血清IL-8、IL-10及TNF-α水平均低于治疗前,且观察组低于对照组,差异均具有统计学意义(P<0.05)。结论臭氧辅治霉菌性阴道炎能有效降低患者血清IL-8、IL-10及TNF-α水平,疗效优于常规治疗,值得临床推广应用。
Objective To observe the effects of ozone supplementation on fungal vaginitis on serum levels of IL-8, IL-10 and TNF-α. Methods 212 cases of fungal vaginitis were randomly divided into observation group and control group of 106 cases. Patients in the control group were treated with dacronide and itraconazole capsules. The observation group was treated with ozone on the basis of the control group. The levels of serum IL-8, IL-10 and TNF-α in two groups before and after treatment were compared. Results The levels of IL-8, IL-10 and TNF-α in the two groups after treatment were lower than those before treatment, and the difference between the two groups was statistically significant (P <0.05). Conclusion Ozone supplementation to treat mycotic vaginitis can effectively reduce the level of serum IL-8, IL-10 and TNF-α, and the curative effect is better than routine treatment, which is worthy of clinical application.