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中西医结合男科疗效机制的研究越来越成为行业的热点。然而,目前许多中西医结合男科疗效机制的研究难以诠释中西医结合男科的内涵,主要体现在不同中医治则、中药复方专方正在进行着作用于同一机制效应指标的重复研究,重病轻证的研究普遍存在,不成熟的证候模型仍成为机制研究的手段,不确定的、不成熟的靶点机制仍成为研究的热点,如此耗费人力物力仍无法诠释男科中医辨证论治的精华及中西医结合辨病辨证取效的机制所在。中西医结合男科疗效机制研究的着眼点要求我们不仅要说明中药复方专方对男科疾病的疗效机制,更重要的是能阐明中医辨证论治的本质。近些年来蛋白质组学、基因组学、转录组学和代谢组学为中西医结合男科病证结合疗效机制研究提供了重要线索,通过对“证”的把握,从宏观整体归纳分析,发展到微观基因、蛋白、代谢、元基因组等角度分析,从而寻求中西医男科病证结合研究的突破口,创新中国特色男科。
Integrative Medicine male mechanism of the effectiveness of the study more and more become a hot industry. However, at present, many studies on the therapeutic mechanism of combined traditional Chinese and western medicine in male are difficult to interpret the connotation of integrated traditional Chinese and western medicine, which is mainly reflected in different TCM principles. Chinese herbal prescriptions are undergoing repetitive researches on the same mechanism effect index, Research on ubiquitous and immature syndromes remains a mechanism for mechanism research. Uncertain and immature target mechanisms are still the focus of research, so the human and material resources are still unable to interpret the essence of TCM syndrome differentiation and the combination of traditional Chinese and western medicine Symptoms of disability effect mechanism lies. Integrative Medicine male mechanism of efficacy of the focus of the study requires that we not only to explain the efficacy of prescriptions for men and women of Chinese medicine mechanism, more importantly, to clarify the essence of traditional Chinese medicine diagnosis and treatment. In recent years, proteomics, genomics, transcriptomics and metabonomics have provided important clues for the study of combined therapeutic effects of integrated traditional Chinese and western medicine in treating male diseases and syndromes. Based on the grasp of “syndromes” and the overall macroeconomic analysis and development To the microscopic genes, proteins, Metabolism, metagenary genome and other perspectives, in order to seek a breakthrough in the combination of Chinese and Western medicine, male disease syndrome, innovation with male Chinese characteristics.