动脉粥样硬化(AS)是 2型糖尿病(T2DM)最常见的并发症。有关AS发病机制的研究主要围绕 3种学说,即脂质浸润学说、血栓形成学说和损伤反应学说。近来Ross[1]在其提出的的损伤反应学说的基础上明确指出:“动脉粥样硬化是一种炎症性疾病而不是单纯由于脂质沉积所致”,而Pickup Atherosclerosis (AS) is the most common complication of type 2 diabetes mellitus (T2DM). Research on the pathogenesis of AS centers on three theories, namely, lipid infiltration theory, thrombosis theory and damage response theory. Recently, Ross [1] made clear on the basis of his theory of damage response that “atherosclerosis is an inflammatory disease rather than simply due to lipid deposition,” while Pickup