目的:探讨急性有机磷农药中毒合并呼吸衰竭的治疗方法。方法:选取2008年1月-2013年6月住我科治疗的急性有机磷农药中毒合并呼吸衰竭患者20例作为本文讨论对象,给予洗胃、应用特效解毒药、血液灌流、对症等治疗措施,并观察其治疗效果。结果:本文20例患者中,19例患者呼吸功能恢复正常,予停用呼吸机辅助通气并拔除气管插管,病情平稳后转内科继续治疗并治愈出院,1例患者因合并循环功能衰竭死亡,抢救成功率95%。结论:对于急性有机磷农药中毒合并呼吸衰竭的患者,尽快清除机体尚未吸收和已经进入血液中的毒物,同时早期、足量、联合、反复使用特效解毒药,可大大提高抢救的成功率。 Objective: To investigate the treatment of acute organophosphorus pesticide poisoning combined with respiratory failure. METHODS: Twenty patients with acute organophosphorus pesticide poisoning and respiratory failure who lived in our department from January 2008 to June 2013 were selected as the object of this study. Gastric lavage, special antidote, hemoperfusion and symptomatic treatment were selected. And observe its therapeutic effect. Results: Of the 20 patients, 19 patients returned to normal respiratory function, ventilator-assisted ventilation was withdrawn and the endotracheal intubation was withdrawn. After the disease was stable, the patient was continued medical treatment and was cured. One patient died of combined circulatory failure, Rescue success rate of 95%. Conclusion: For acute organophosphorus pesticide poisoning patients with respiratory failure, as soon as possible to remove the body has not absorbed and has entered the blood of toxic substances, early, adequate, combined, repeated use of special antidote, can greatly improve the success rate of rescue.