非甾消炎药——布洛芬的合成方法

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非甾消炎镇痛解热药布洛芬[2-(4′-异丁苯基)-丙酸;“Brufen”]由于其疗效确实,副作用小,适宜于长期服用,在治疗风湿性关节炎等炎症疾病方面获得了较好的声誉,引起了国内外医药界的广泛重视。此药于1969年首先在英国上市,此后,日本、加拿大、西德、美国等国家相继生产上市,产 Non-steroidal anti-inflammatory analgesic antipyretics ibuprofen [2- (4’-isobutylphenyl) -propionic acid; “Brufen”] Because of its efficacy, side effects, suitable for long-term use in the treatment of rheumatoid arthritis And other inflammatory diseases have gained a good reputation, aroused widespread attention at home and abroad in the pharmaceutical industry. The drug was first listed in the UK in 1969, after which Japan, Canada, West Germany, the United States and other countries have been listed on the production
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