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[目的]评估第7版UICCTNM分期系统对胃癌患者预后的预测价值。[方法]回顾性分析浙江大学医学院附属第二医院2003年6月至2005年9月行手术切除且资料齐全的胃癌136例,按照第7版TNM分期,预后指标行Kaplan-Meier分析,选择有显著差异指标行Cox多因素分析。[结果]胃癌患者5年生存率为40.0%。单因素分析发现手术方式、浸润深度、淋巴结转移数目、第7版TNM分期是预后影响因素。多因素分析结果显示浸润深度、第7版TNM分期、手术方式是影响预后的独立危险因素。第6版中N1拆分为第7版的N1和N2两组,5年生存率分别为48.2%和31.1%(P=0.000)。[结论]第7版TNM分期系统能准确预测胃癌预后。
[Objective] To evaluate the prognostic value of the 7th edition UICCTNM staging system in patients with gastric cancer. [Methods] A retrospective analysis of 136 cases of well-resected gastric cancer with complete data from the Second Affiliated Hospital of Zhejiang University School of Medicine from June 2003 to September 2005 was performed according to the seventh edition of TNM staging and prognostic indicators of Kaplan-Meier analysis There are significant differences in the index line Cox multivariate analysis. [Results] The 5-year survival rate of gastric cancer patients was 40.0%. Univariate analysis revealed that surgical modality, depth of invasion, number of lymph node metastases, and stage 7 TNM staging were prognostic factors. Multivariate analysis showed that the depth of invasion, the seventh edition of TNM staging, surgical methods are independent prognostic risk factors. In the 6th edition, N1 was divided into N1 and N2 in the 7th edition. The 5-year survival rates were 48.2% and 31.1% respectively (P = 0.000). [Conclusion] The 7th edition of TNM staging system can accurately predict the prognosis of gastric cancer.