目的探讨甲亢患者骨代谢的特点及影响因素。方法应用国产单光子骨密度仪测定７３例甲亢患者骨密度，同时测定多种骨代谢指标。结果甲亢患者骨密度明显低于正常对照组（Ｐ＜００１）；骨钙素（Ｐ＜００１）和碱性磷酸酶（Ｐ＜００５）明显高于正常，且与骨密度呈明显负相关。结论甲亢患者骨转化活跃，有明显的骨质疏松症倾向。 Objective To investigate the characteristics and influencing factors of bone metabolism in patients with hyperthyroidism. Methods Bone mineral density (BMD) was measured in 73 cases of hyperthyroidism patients by using single-photon bone density analyzer. Meanwhile, various indexes of bone metabolism were measured. Results The bone mineral density of patients with hyperthyroidism was significantly lower than that of the normal control group (P <001). The levels of osteocalcin (P <001) and alkaline phosphatase (P <005) were significantly higher than those of normal controls Significantly negative correlation. Conclusion Hyperthyroidism patients with active bone turnover, there is a clear tendency of osteoporosis.