19世纪初,人们已注意到有发热、心脏杂音、脾脏肿大三个主要体征的特殊疾病,当时病因还不明确,几乎所有的病例均死亡。其后由于细菌学检验的进步,明确了病因,再加上青霉素的发明,提高了本病的治愈率。过去根据临床经过,本症分为急性细菌性心内膜炎(ABE)和亚急性细菌性心内膜炎(SBE)两种病型,使人们在与病原菌相对应的基础上来理解病情和经过的不同。近年来由于高效的抗生素、肾上腺皮质激素、免疫抑制剂、抗癌药物的应用,改变了本病的临床经过,另一方面又发现了由细 The early 19th century, people have noticed the fever, heart murmur, splenomegaly three major signs of special diseases, the etiology is not clear, almost all cases of death. Later, due to the progress of bacteriological tests, a clear cause, coupled with the invention of penicillin, increased the cure rate of the disease. In the past, according to clinical experience, the disease is divided into two types of acute bacterial endocarditis (ABE) and subacute bacterial endocarditis (SBE), so that people in accordance with the pathogen to understand the condition and after s difference. In recent years due to efficient antibiotics, adrenal cortical hormones, immunosuppressive agents, anti-cancer drugs, changed the clinical course of the disease, on the other hand found by the fine