患者，女性，35岁。1993年10月因感冒自服感冒通2片后，双下肢皮肤出现紫癜样皮疹，伴浮肿，尿常规检查异常。诊断为急性肾炎，先后应用强的松、氢化考的松、青霉素、氢等青霉素消疗1月余无效，皮疹增多并遍布全身．颜面肿胀，睁眼困难，伴恶心、呕吐。实验室检查：BUN、Cr明显 Patient, female, 35 years old. In 1993 October due to cold self-service influenza through 2, purpura-like skin rash on both lower extremities, with edema, urine routine examination abnormalities. Diagnosis of acute nephritis, has the application of prednisone, hydrocortisone, penicillin, hydrogen and other penicillin treatment more than 1 month ineffective, increased rash and throughout the body. Face swelling, eyes open difficulties, with nausea, vomiting. Laboratory tests: BUN, Cr significantly