秋水仙碱致剥脱性皮炎1例

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患者,男,58,因“痛风”,首服秋水仙碱1mg×2片,约0.5h 后感到脸部皮肤发痒,0.5h 后又继服秋水仙碱1mg×1片,约0.5h 后觉得全身皮肤搔痒,并出现散在性大小不等的红色风团,继而出现胸闷、气急,即来院急诊。体检:神志清,心率100次/min,血压135/85mmHg,体温37℃,立即肌注盐酸肾上腺素0.5mg,静推50% GS 40ml 加地塞米松5mg,吸氧,20min 后,气急、胸闷症状减轻,1h 后,症状消失。加服息斯敏、强的松片。d2患者全身皮肤呈现潮红一片,痒伴胀痛感,实验室检查 WBC 13200/mm~3,N76%,L24%,T37.6℃,经抗菌+ Patients, male, 58, due to “gout”, the first service colchicine 1mg × 2 tablets, about 0.5h after itching of the skin of the face, after 0.5h and then take colchicine 1mg × 1 tablets, after about 0.5h Feel the whole body itchy skin, and scattered scattered in the size of the red wind group, followed by chest tightness, shortness of breath, that is hospital emergency. Physical examination: conscious mind, heart rate 100 beats / min, blood pressure 135 / 85mmHg, body temperature 37 ℃, immediately intramuscular injection of epinephrine hydrochloride 0.5mg, 50% GS 40ml static push plus dexamethasone 5mg, oxygen, 20min, Reduce, 1h, the symptoms disappear. Plus serving asosim, strong loose tablets. d2 patients with a flush of whole body skin, itching accompanied by pain, laboratory tests WBC 13200 / mm ~ 3, N76%, L24%, T37.6 ℃, antibacterial +
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