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目的评价经阴道超声(TVS)检查卵巢形态学特征、卵巢间质内血流动力学结合血激素水平在多囊卵巢综合征(PCOS)诊断中的价值。方法采用经阴道超声对35例PCOS患者的卵巢进行形态学和卵巢间质内血流动力学的观察和测量,同时检测血液中卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E_2)及睾酮(TESTO)的水平,设立正常对照组30例进行对比分析。结果 PCOS患者卵巢体积(OV)、卵泡数(FN)、卵巢间质面积(SA)、卵巢间质面积/总面积(SA/TA)较正常对照组明显增高(P<0.05,P<0.01);其中SA/TA的敏感性和特异性最高;PCOS患者卵巢间质内血流阻力明显减低,同时血液中睾酮激素水平明显高于正常组(P<0.01)。结论通过阴道超声检测卵巢形态学特征、卵巢间质内血流阻力变化并结合血液中睾酮激素水平,有助于提高经阴道超声诊断多囊卵巢综合征的敏感性及特异性,并可作为多囊卵巢综合征治疗随访的重要评价指标。
Objective To evaluate the value of transvaginal ultrasonography (TVS) in morphological features of ovarian and serum levels of ovarian interstitial hemodynamics in the diagnosis of polycystic ovary syndrome (PCOS). Methods Transvaginal ultrasonography was used to observe the morphology and ovarian interstitial hemodynamics in 35 cases of PCOS patients. The blood levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol Alcohol (E_2) and testosterone (TESTO), and 30 normal control subjects were established for comparative analysis. Results The ovarian volume (OV), number of follicles (FN), ovarian stromal area (SA) and ovarian interstitial area / total area (SA / TA) in PCOS patients were significantly higher than those in normal controls (P < ; SA / TA sensitivity and specificity of the highest; PCOS ovarian interstitial blood flow resistance was significantly reduced, while blood testosterone levels were significantly higher than the normal group (P <0.01). Conclusions Transvaginal sonography can detect ovarian morphological features, changes in blood flow resistance in the ovarian interstitium and combine with testosterone levels in the blood to improve the sensitivity and specificity of transvaginal sonography in the diagnosis of PCOS. Follow-up of cystic ovarian syndrome is an important evaluation index.