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目的:探讨中药外敷联合泡沫硬化剂治疗下肢静脉曲张的疗效和安全性。方法:纳入下肢静脉曲张患者100例,按照就诊顺序编号随机分为单纯泡硬化组和联合治疗组。单纯硬化治疗组:单纯使用聚桂醇泡沫硬化剂治疗曲张静脉,术后穿医用弹力袜。联合治疗组:泡沫硬化治疗同前,术后第3天开始一日两次软坚散结方外敷硬结或纤维条索处,平均外敷21d。结果:所有患者随访5-10个月,平均7个月。单纯泡沫硬化组显效45例,有效5例,总有效率100%,联合治疗组显效48例,有效2例,总有效率100%,2组疗效及术后复发率比较差异无显著性(P>0.05);两组并发症发生率分别为35.0%和11.3%,比较差异有显著性(P=0.000)。结论:与单纯泡沫硬化治疗比较,中药外敷联合泡沫硬化剂治疗下肢静脉曲张可明显降低并发症的发生,但疗效并无显著差异。
Objective: To investigate the curative effect and safety of traditional Chinese medicine combined with foam sclerosing agent in the treatment of varicose veins of the lower extremities. Methods: A total of 100 patients with varicose veins of lower extremities were enrolled and randomly divided into simple bubble sclerosis group and combination therapy group according to the order of treatment. Simple sclerosis treatment group: simple use of lauryl alcohol foam sclerotherapy varicose veins, postoperative medical elastic stockings. Combination therapy group: foam sclerosis treatment with the same, the first three days after the operation began twice daily topical scleroderma or fibrous cords, external topical 21d. Results: All patients were followed up for 5-10 months with an average of 7 months. Simple foam sclerosis group markedly effective in 45 cases, effective in 5 cases, the total effective rate was 100%, 48 cases in the combined treatment group markedly effective in 2 cases, the total effective rate was 100%, two groups of curative effect and postoperative recurrence rate was no significant difference (P > 0.05). The complication rates of the two groups were 35.0% and 11.3% respectively, with significant difference (P = 0.000). Conclusion: Compared with simple foam sclerotherapy, external application of Chinese medicine combined with foam sclerotherapy of varicose veins can significantly reduce the incidence of complications, but the effect was no significant difference.