人类核仁组织者区(NOR)位于13、14、15和21、22这五对近端着丝粒染色体的副缢痕处。应用银染技术可使具有活性的NOR 特异性着色。Miller DA 等发现,只有在功能上有活性的rRNA 基因才能被银染,银染的NOR 的数量与细胞中具有转录活性的rRNA基因相关。Miller 和Lernia 等认为,近端着丝粒染色体参与联合的频率与它们NOR 的 The human nucleolar organizer region (NOR) is located at the paternity mark of the five pairs of proximal centromeric chromosomes, 13,14,15 and 21,22. The use of silver staining technology allows the activity of NOR-specific coloring. Miller DA et al. Found that only functionally active rRNA genes can be silver-stained, and the amount of silver-stained NOR correlates with transcriptionally active rRNA genes in cells. Miller and Lernia so that the near-centromeric chromosomes involved in the frequency of their association with NOR