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胰岛素样生长因子系统 (IGFs)是卵巢局部诸多调节系统中重要的因素之一,以自分泌、旁分泌方式参与卵泡发育、优势卵泡选择及排卵。胰岛素样生长因子 I(IGF I)可以调节卵泡发育及卵巢性激素的合成 [1, 2]。因此,IGF I在多囊卵巢综合征(PCOS)病理生理机制中的作用受到关注。
Insulin-like growth factor system (IGFs) is one of the most important factors in ovarian local regulation system. It participates in follicular development, superior follicle selection and ovulation in an autocrine and paracrine way. Insulin-like growth factor I (IGF I) regulates follicular development and ovarian sex hormone synthesis [1, 2]. Therefore, the role of IGF I in the pathophysiology of polycystic ovary syndrome (PCOS) is of concern.