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抗原处理相关转运体 (TAP)属于ABC(ATP bindingcas sette)转运体超家族B亚家族。人类TAP基因位于 6号染色体上的MHC II类基因区 ,其编码的TAP1和TAP2分子 ,分别由 74 8和 6 86个氨基酸残基所组成 ,两者可形成异源二聚体参与肽类的转运过程 ,在MHC I类分子介导的抗原递呈途径中?
Antigen handling related transporters (TAPs) belong to the ABC (ATP bindingcas sette) transporter superfamily B subfamily. Human TAP gene is located on chromosome 6 MHC class II gene region, which encodes TAP1 and TAP2 molecules, respectively, by 74 8 and 6 86 amino acid residues, both can form heterodimers involved in the peptide Transport process, MHC class I molecule-mediated antigen presentation pathway?