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我院自1984年2月～1992年2月采用体外配合腔内放疗及盒式四野外放疗两种方式治疗子宫颈癌,现已随访5年以上。目的是判明两种方式的治疗效果及生存质量。体外配合腔内放疗先给盆腔前后大野外放疗46Gy,此后中间挡铅4cm外照射14～20Gy同时每周后装腔内放疗一次(当日不做外照射)A点18～24Gy。盒式四野外放疗采用盆腔前后野及两侧野共四野外放疗轮照总剂量60～65Gy,然后缩野外照射10～12Gy。结果:两组的5年生存率各为77%、51%;2年局部及盆腔病灶复发率各为125%、30%;2年远处转移率各为175%、37%;5年后的各种并发症百分率等均有显著差异(P<001～005)。体外配合腔内放疗治疗子宫颈癌其治疗效果及生存质量显著优于盒式四野外放疗。
Our hospital from February 1984 to February 1992 with in vitro with intracavitary radiotherapy and box four field radiotherapy two ways to treat cervical cancer, has been followed for more than 5 years. The purpose is to determine the two ways of treatment and quality of life. In vitro with intracavitary radiotherapy before and after the great pelvic radiotherapy 46Gy, after the middle of the block 4cm lead 14 ~ 20Gy external radiation at the same time every week after the cavity radiotherapy (the same day do not do external irradiation) A point 18 ~ 24Gy. Box four field radiotherapy using the pelvic anteroposterior and lateral fields on both sides of a total of four field radiotherapy wheel total dose of 60 ~ 65Gy, and then reduce the field 10 ~ 12Gy. Results: The 5-year survival rates of two groups were 77% and 51% respectively. The recurrence rates of local and pelvic lesions in 2 years were 125% and 30% respectively. The distant metastasis rates in 2 years were 175% and 37% respectively. After 5 years The percentage of various complications were significantly different (P <001 ~ 005). In vitro with intracavitary radiotherapy for cervical cancer treatment and quality of life was significantly better than the cassette four field external beam radiotherapy.