震颤麻痹是一种锥体外系的变性病。发病原因与黑质—纹状体多巴胺神经通路的功能发生障碍有关,其主要症状为震颤、肌僵直和运动障碍。 近发现,脑基底神经节内的r-氨基丁酸(GABA)能神经、多巴胺能神经、乙酰胆碱能神经之间亦存在着相互联系与制约的关系(见图)。据认为此处r-氨基丁酸能神经功能失调也是产生震颤麻痹的原因之一。 Parkinsonism is an extrapyramidal degenerative disease. The pathogenesis is related to the dysfunction of the substantia nigra and striatal dopamine neural pathway, the main symptoms of which are tremors, muscle rigidity and dyskinesia. Recently found that basal ganglia r-aminobutyric acid (GABA) can be nerve, dopaminergic nerve, acetylcholinergic nerve there is also a relationship between the relationship and constraints (see Figure). It is thought that r-aminobutyric acid can be one of the causes of paralysis.