G蛋白偶联受体在心肌生长和收缩功能的调节中起重要作用 ,肾上腺素受体自身又被一系列特异性激酶所调控 ,这类激酶称为G蛋白偶联受体激酶。随着转基因鼠模型的发展和建立 ,对调控心血管系统的肾上腺素受体信号转导系统有了进一步认识。 G protein-coupled receptors play an important role in the regulation of myocardial growth and contractile function, and the adrenergic receptor itself is regulated by a series of specific kinases, which are called G-protein coupled receptor kinases. With the development and establishment of transgenic mouse models, further understanding has been made on the adrenergic receptor signaling system that regulates the cardiovascular system.