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目的:探讨高脂血症家兔对肺动脉的影响。方法:对40只家兔实验性动脉粥样硬化的肺动脉血管及分支和肺组织进行病理组织学观察。结果:结果表明,除检出家兔主动脉和冠状动脉粥样硬化外,全部受试家兔(100%)检出不同程度以脂质斑块为主的肺动脉粥样硬化,间质性肺炎23例(57.5%)和胆固醇性肉芽肿性肺炎5例(12.5%)。结论:高胆固醇血症不仅可以诱发家兔主动脉和冠状动脉的粥样硬化,同时也可产生肺动脉粥样硬化和肺的炎症病变。提示,在临床冠心病防治中,这些严重合并症也应加以重视。
Objective: To investigate the effect of hyperlipemia rabbits on pulmonary artery. Methods: The histopathological changes of pulmonary arteries, branches and lungs of 40 rabbits with experimental atherosclerosis were observed. Results: The results showed that in addition to the detection of aortic and coronary atherosclerosis in rabbits, all tested rabbits (100%) detected pulmonary plaque-predominant pulmonary atherosclerosis, interstitial pneumonia 23 cases (57.5%) and 5 cases of cholesterol granulomatous pneumonia (12.5%). Conclusion: Hypercholesterolemia not only induces the atherosclerosis of the aorta and coronary arteries in rabbits, but also produces atherosclerosis of the lungs and inflammation of the lungs. Tip, in clinical prevention and treatment of coronary heart disease, these serious complications should also be taken seriously.