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目的:探讨显微外科手术治疗脑胶质瘤的临床效果。方法:选取2018年3月至2019年3月北部战区总医院神经外科收治的45例脑胶质瘤患者，男25例，女20例。年龄(45.02±2.57)岁，年龄范围为23～61岁。根据不同的肿瘤部位选择不同的手术入路，对所有患者手术前后的临床症状、生活质量评分以及术后不良反应发生情况进行观察。结果:41例颅内压升高患者，全部得到完全缓解；36例脑神经功能障碍患者中，完全缓解34例，部分缓解2例。24例癫痫患者中，完全缓解23例，部分缓解1例；30例语言运动与感觉功能障碍患者中，完全缓解28例，部分缓解2例。术后6个月、术后12个月分别与术前相比、术后12个月与术后6个月相比，躯体功能、认知功能、角色功能、情绪功能、社会功能评分均升高，差异有统计学意义(n P<0.05)。术后无感染，1例患者出现肌力降低及运动型失语，经治疗得到缓解。n 结论:显微外科手术治疗脑胶质瘤明显改善了临床症状，提高了生活质量评分，术后不良反应发生情况较少。“,”Objective:To investigate the clinical effect of microsurgery in the treatment of glioma.Methods:A retrospective study was performed on 45 patients with glioma who were admitted to the department of Neurosurgery, General Hospital of Northern Theater Command from March 2018 to March 2019, including 25 males and 20 females, aged (45.02±2.57) years old, ranging 23 to 61 years old.According to different tumor sites.The improvement of clinical symptoms, quality of life score and postoperative adverse reactions of all patients were observed.Results:All the 41 patients with elevated intracranial pressure were completly relieved; among the 36 patients with cerebral nerve dysfunction, 34 patients had complete remission and 2 patients had partial remission.Among the 24 patients with epilepsy, 23 patients received complete remission and 1 patient received partial remission; among the 30 patients with speech, motor and sensory dysfunction, 28 patients had complete remission and 2 patients had partial remission.Somatic function, cognitive function, role function, emotional function and social function were all increased at 6 months and 12 months after surgery, respectively, compared with those before surgery and 12 months after surgery, and the differences between groups were statistically significant (n P<0.05). Postoperative infection was not found in 1 patient, and 1 patient had reduced muscle strength and motility aphasia.n Conclusion:Different microsurgical approaches combined with different tumor sites can significantly improve the clinical symptoms, improve the quality of life score, and lower the incidence of postoperative adverse events.