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目的观察口服胺碘酮和厄贝沙坦在心房颤动复律后维持窦性心律的疗效。方法非永久性心房颤动患者79例,成功转复窦性心律后随机分为两组:胺碘酮组(A组)40例和胺碘酮联用厄贝沙坦组(B组)39例。随访18个月,观察两组窦性心律维持率和房颤复发中位时间。结果A组和B组维持窦性心律的有效率分别为57.5﹪和79.5﹪,B组房颤复发中位时间明显延长,两组差异有统计学意义。结论胺碘酮联用厄贝沙坦可降低心房颤动复发率,更有效地维持心房颤动转复后的窦性心律。
Objective To observe the efficacy of oral amiodarone and irbesartan to maintain sinus rhythm after cardioversion of atrial fibrillation. Methods A total of 79 patients with non-permanent atrial fibrillation (AF) were randomly divided into two groups: amiodarone group (A group), amiodarone group (n = 40) and irbesartan group (group B) . After 18 months of follow-up, the maintenance rate of sinus rhythm and the median time of atrial fibrillation recurrence were observed. Results The effective rates of maintaining sinus rhythm in group A and group B were 57.5% and 79.5%, respectively. The median time to recurrence of atrial fibrillation in group B was significantly longer than that in group B. The difference between the two groups was statistically significant. Conclusion Amiodarone combined with irbesartan can reduce the recurrence rate of atrial fibrillation and more effectively maintain sinus rhythm after atrial fibrillation.