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目的 探讨妊高征血液粘度、过氧化脂质（ＬＰＯ）水平的变化及 两者的相关性。方法 随机选择妊高征患者４０例（妊高征组）、正常晚期妊娠妇女 ３０例（正常孕妇组），用硫代巴比妥酸比色法测定全血ＬＰＯ水平，用粘度计测定高 切、低切变率全血粘度及血浆粘度，分析血液粘度各指标与ＬＰＯ水平的关系。结果 妊高征组的低切、高切全血粘度、血浆粘度及 ＬＰＯ水平均显著高于正常孕妇组 （Ｐ＜０．０５，Ｐ＜０．０１）。且妊高征患者的高切粘度与血中ＬＰＯ水平呈正相关。结论 妊高征患者全血粘度水平升高与其体内脂质过氧化反应增强有关，测定血液粘 度水平有助于指导临床治疗。
Objective To investigate the changes of blood viscosity and lipid peroxidation (LPO) levels in pregnancy induced hypertension and their relationship. Methods 40 cases of pregnancy induced hypertension (PIH) group and 30 normal pregnant women (normal pregnant women group) were randomly selected, LPO level in whole blood was measured by thiobarbituric acid colorimetric method, , Low shear rate whole blood viscosity and plasma viscosity, analyze the relationship between each index of blood viscosity and LPO level. Results The levels of low cut and high cut whole blood viscosity, plasma viscosity and LPO in PIH group were significantly higher than those in normal pregnant group (P <0.05, P <0.01). PIH patients with high shear viscosity and blood LPO levels were positively correlated. Conclusion The increase of whole blood viscosity in patients with PIH is related to the increase of lipid peroxidation in vivo. The determination of blood viscosity can help to guide the clinical treatment.