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目的观察急性心力衰竭患者血浆氨基末端脑利钠肽前体(NT-proBNP)的水平及其与心房纤颤的关系。方法 60例急性心力衰竭患者按房颤、窦性心率分组,采用免疫荧光法测定血浆NT-proBNP水平。结果急性心力衰竭合并房颤组患者血浆NT-proBNP水平明显高于窦性心率组(P<0.05)。结论急性心力衰竭患者的NT-proBNP水平,合并房颤者比窦性心率者高,且与左房内径有明显相关性。
Objective To observe the level of plasma NT-proBNP (A-terminal proBNP) in patients with acute heart failure and its relationship with atrial fibrillation. Methods Sixty patients with acute heart failure were divided into groups according to atrial fibrillation and sinus rhythm. Plasma NT-proBNP levels were measured by immunofluorescence. Results The plasma levels of NT-proBNP in patients with acute heart failure and atrial fibrillation were significantly higher than those in sinus heart rate group (P <0.05). Conclusions NT-proBNP levels in patients with acute heart failure and those with atrial fibrillation are higher than those in sinus rhythm, and are significantly associated with left atrial diameter.