【摘 要】
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Over evolution,the human species has acquired higher cognitive function,which helps to distinguish Homo sapiens from other mammals.Particularly,humans have a large neocortex through the evolutionary expansion of the brain,which is believed to be instrumen
【机 构】
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Department of Anesthesia,The State Key Laboratory of Medical Neurobiology and MOE Frontiers Center f
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Over evolution,the human species has acquired higher cognitive function,which helps to distinguish Homo sapiens from other mammals.Particularly,humans have a large neocortex through the evolutionary expansion of the brain,which is believed to be instrumental in the estab-lishment of comprehensive neuronal circuits [1,2].A hallmark of the human brain is the highly convoluted brain surface structure,named gyrification or cortical folding,consisting of gyri and sulci,which significantly increase the cortical surface area.However,the mechanisms underlying the cortical expansion remain elusive.
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