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本文应用单因素和多元条件Logistic回归模型配合相结合的统计分析技术,进一步对广西原发性肝细胞癌的病因进行综合研究。结果表明,乙肝病毒血清学标志抗—HBc、10年前吃玉米占口粮比例和微量元素Se/Cu比值是广西原发性肝细胞癌的三大重要致病因素,而10年前饮用塘沟水、肝癌或肝病家族史、5年前肝病史是次要或辅助的致癌因子。综合本研究结果提示:广西原发性肝细胞癌是多因素综合作用的可能性大。
In this paper, a univariate and multivariate conditional Logistic regression model combined with statistical analysis techniques are used to further comprehensively investigate the etiology of primary hepatocellular carcinoma in Guangxi. The results showed that the anti-HBc serological markers of hepatitis B virus, the proportion of rations eaten corn 10 years ago, and the Se/Cu ratio of trace elements were the three most important pathogenic factors for primary hepatocellular carcinoma in Guangxi. A family history of water, liver or liver disease, and a history of liver disease 5 years ago were secondary or secondary carcinogens. Comprehensive results of this study suggest that Guangxi’s primary hepatocellular carcinoma is likely to have a combination of multiple factors.