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炔雌醚(Quinestrol,商品名Estrovis)是一种口服有效的雌激素,作为替代治疗每周仅服用1次,最近美国已有销售。可用于迅速缓解绝经期子宫内膜兴奋低下引起的症状。药理和剂量:炔雌醚为乙炔雌二醇-3-环戊醚。本品从胃肠道吸收后储存在人体脂肪组织中,然后慢慢释放出来,并代谢为乙炔雌二醇,本品每日1mg连服4天,其抑制促卵泡成熟激素及促性腺激素的作用可维持3个月之久。推荐剂量为每日0.1mg,连服7天,隔1周后,每周0.1mg;如症状不消失,剂量可增加到每周0.2mg。临床试验:按推荐剂量采用炔雌醚的研究报道
Quinestrol (Quinestrol, trade name Estrovis) is an orally available estrogen that is taken as a replacement therapy only once a week and has recently been marketed in the United States. Can be used to quickly relieve menopausal symptoms caused by low endometrial excitability. Pharmacology and Dose: Ethinyl estradiol is ethinyl estradiol-3-cyclopentyl ether. This product is absorbed from the gastrointestinal tract stored in human adipose tissue, and then slowly released and metabolized to ethinyl estradiol, daily 1mg of the goods even for 4 days, which inhibits follicle stimulating hormone and gonadotropin Role can be maintained for 3 months. The recommended dose of 0.1mg daily, and even serving 7 days, every 1 week, 0.1mg per week; if the symptoms do not disappear, the dose can be increased to 0.2mg per week. Clinical trials: According to the recommended dose of ethinylestradiol research reports