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尿毒症患者为细菌感染的高危人群,头孢吡肟为第四代头孢菌素,杀菌力强,抗菌谱广,不良反应少,广泛用于各种感染性疾病的治疗[1]。但尿毒症患者对抗生素的吸收、分布、代谢与正常人不同,易导致血液中药物或其代谢产物蓄积。回顾我院2006年4月至2008年7月门诊及住院10例尿毒症患者
Uremic patients with high risk of bacterial infection, cefepime as the fourth generation cephalosporin, bactericidal power, broad antibacterial spectrum, less adverse reactions, is widely used in the treatment of various infectious diseases [1]. However, patients with uremia absorption of antibiotics, distribution, metabolism and normal different, easily lead to the accumulation of blood drugs or their metabolites. Review our hospital from April 2006 to July 2008 outpatient and inpatient 10 cases of uremic patients