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目的:观察脑出血是否能引起心电图(ECG)异常。方法:56只Wistar大鼠随机分为3组:对照组10只,左侧内囊血肿组22只,右侧内囊血肿组24只。麻醉后,用监护仪监测动物的ECG,将120μl新鲜鼠血注入大鼠内囊处,观察其ECG变化。结果:右侧内囊血肿组的ECG异常发生率为62.5%(15/24),左侧内囊血肿组为36.4%(8/22),2组无统计学差异(χ2=3.0057,P>0.05)。ECG异常表现为ST段上抬(24/46)、心房扑动(12/46)和频发室性早搏(7/46)。70.8%鼠(17/24)的ECG异常发生在内囊血肿形成后3小时内。对照组在监测过程中未发现ECG异常。结论:内囊血肿可引起ECG异常。
Objective: To observe whether cerebral hemorrhage can cause electrocardiogram (ECG) abnormalities. Methods: Fifty-six Wistar rats were randomly divided into three groups: control group (n = 10), left inner capsule hematoma group (n = 22) and right right inner capsule hematoma group (n = 24). After anesthesia, monitor the ECG of the animal and inject 120 μl of fresh rat blood into the internal capsule of the rat to observe the ECG changes. Results: The incidence of ECG abnormalities in the right internal cyst hematoma group was 62.5% (15/24), in the left cyst hematoma group was 36.4% (8/22), there was no significant difference between the two groups (χ2 = 3.0057, P> 0.05). ECG abnormalities were ST-segment elevation (24/46), atrial flutter (12/46) and frequent premature ventricular contractions (7/46). An abnormality of the ECG in 70.8% of the rats (17/24) occurred within 3 hours after the formation of the internal capsule hematoma. The control group did not detect ECG abnormalities during the monitoring. Conclusion: Internal capsule hematoma can cause ECG abnormalities.