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目的分析济南市城区健康成年男性骨密度的变化规律,为防治男性骨质疏松提供依据。方法 2007年1月至2010年7月,随机抽取济南市城区的3个社区、1 214名健康成年男性为研究对象,20～90岁,平均(57.3±16.0)岁。采用DPX-NT双能X线骨密度测量仪检测腰椎1～4、股骨颈、Word’s三角区、大转子和全股骨的骨密度。结果腰椎1～4、股骨颈、Word’s三角区、大转子和全股骨的骨密度在20～35岁随年龄增长逐渐增加,35～39岁增长较快并达到峰值,股骨颈在70～74岁骨量丢失加速,80～84岁股骨颈、Word’s三角区、大转子、全股骨骨密度累积丢失率最大分别为18.71%、29.82%、13.73%和14.8%。70～79岁和80～89岁骨质疏松的发生率为15.1%和29.4%。结论本研究获得济南城区健康男性腰椎及股骨的骨量峰值,70～74岁骨量快速丢失,70岁后骨质疏松发生率显著上升。
Objective To analyze the variation of bone mineral density (BMD) in healthy adult men in urban area of Jinan City, and provide evidence for prevention and treatment of osteoporosis in men. Methods From January 2007 to July 2010, randomly selected 3 communities in urban area of Jinan City, 1 214 healthy adult male subjects, 20 to 90 years old, with an average of (57.3 ± 16.0) years. Bone mineral density (BMD) of lumbar spine 1 ~ 4, femoral neck, Word’s triangle area, big trochanter and total femur was detected by DPX-NT dual-energy X-ray absorptiometry. Results BMD of lumbar vertebra 1-4, femoral neck, Word’s triangle area, greater trochanter and total femur increased with age from 20 to 35 years old. The bone mineral density peaked at 35-39 years old and peaked at 70-74 years The loss of bone mass accelerated. The cumulative loss of BMD of 80-84 year-old femoral neck, Word’s triangle area, greater trochanter and total femur were 18.71%, 29.82%, 13.73% and 14.8% respectively. Osteoporosis rates were 70% to 79 years and 80 to 89 years, with 15.1% and 29.4%, respectively. Conclusions In this study, the bone mass peak value of lumbar and femur in healthy urban area of Jinan city was obtained. The bone mass was rapidly lost from 70 to 74 years old, and the incidence of osteoporosis increased significantly after 70 years of age.