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通过报道临床十二指肠癌患者使用奥沙利铂为主方案化疗后出现暴发性肝炎病例1例,探讨FOLFOX化疗药物罕见不良反应的发生机制,指导临床使用FOLFOX方案治疗肿瘤过程中预防暴发性肝炎和肝功能损伤的发生。
One case of fulminant hepatitis was reported after oxaliplatin-based chemotherapy was reported in clinical patients with duodenal cancer. The mechanism of rare adverse reactions of FOLFOX chemotherapeutic drugs was discussed to guide the clinical use of FOLFOX regimen in the prevention of fulminant Hepatitis and liver damage.