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目的:观察归芍六君子汤联合西药治疗肝硬化的临床疗效。方法:将本院82例肝硬化患者随机分为研究组和对照组各41例。对照组给予常规西药治疗,研究组在常规西药治疗基础上加用归芍六君子汤,对比2组肝功能指标变化情况与临床疗效。结果:总有效率研究组为95.12%,对照组为70.73%,2组比较,差异有统计学意义(P<0.05);治疗后,研究组的中医证候积分、Child肝功能分级积分、肝功能检查指标[谷丙转氨酶(ALT)、谷草转氨酶(AST)、谷氨酰转移酶(GGT)及总胆红素(TBil)]均低于对照组(P<0.05)。结论:归芍六君子汤联合西药治疗肝硬化能够有效改善患者的临床症状及肝功能,且无明显不良反应,是一种较为理想的治疗方案。
Objective: To observe the therapeutic effect of Guishao Liujunzi Decoction combined with western medicine on cirrhosis. Methods: 82 patients with cirrhosis in our hospital were randomly divided into study group and control group, 41 cases each. The control group was given conventional Western medicine. The research group added Guishao Liujunzi Decoction on the basis of routine Western medicine, comparing the changes of liver function indexes and clinical curative effect in the two groups. Results: The total effective rate was 95.12% in the study group and 70.73% in the control group. There was significant difference between the two groups (P <0.05). After treatment, TCM syndrome score, Child’s liver function score, Function indexes (ALT, AST, GGT and total bilirubin) were lower than those of the control group (P <0.05). Conclusion: Guishao Liujunzi Decoction combined with Western medicine in the treatment of cirrhosis can effectively improve the clinical symptoms and liver function in patients without obvious adverse reactions, which is an ideal treatment.