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目的 :探讨气管内冲洗的时机对羊水Ⅲ度胎粪污染新生儿预后的影响 ,以期降低胎粪吸入综合征 (MAS)的发病率 ,减少并发症。方法 :对 1998年 5月至 2 0 0 2年 5月我院收治的 5 0例有Ⅲ度羊水污染新生儿的临床资料进行回顾性分析。结果 :在 32例本院产科出生时立即进行气管内冲洗的患儿中 ,发生MAS 15例 ,其中轻型 11例 ,重型 4例 ,无极重型患儿 ;而从外院转来后再进行气管内冲洗的 18例患儿中 ,发生MAS 14例 ,其中轻型 5例 ,重型 7例 ,极重型 2例。前者MAS发病率为4 6 9% ,后者为 77 8%。二者比较存在显著性差异 (P <0 0 5 )。结论 :对Ⅲ度羊水污染新生儿出生时立即进行气管内冲洗能有效减少MAS的发生和发展
Objective: To investigate the effect of timing of endotracheal flushing on the prognosis of third trimester meconium-stained amniotic fluid in neonates in order to reduce the incidence of meconium aspiration syndrome (MAS) and reduce the complications. Methods: The clinical data of 50 newborn infants with grade III amniotic fluid admitted to our hospital from May 1998 to May 2002 were analyzed retrospectively. Results: Of the 32 infants with immediate endotracheal intubation at birth, 15 cases of MAS occurred, of which 11 were mild, 4 were severe, and children of non-maximal polarity were treated with endotracheal irrigation Of the 18 children, 14 were MAS, of which 5 were light, 7 were severe and 2 were very severe. The former incidence of MAS was 46.9% and the latter was 77.8%. There was significant difference between the two (P <0 05). Conclusion: Immediate intratracheal flushing of newborns with Ⅲ degree amniotic fluid contamination can effectively reduce the occurrence and development of MAS