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目的探讨头孢米诺钠在糖尿病合并社区获得性下呼吸道感染治疗中的应用效果,为该病的治疗提供参考依据。方法选取医院2014年1月-2015年6月80例糖尿病合并社区获得性下呼吸道感染患者作为研究对象,将其随机分为研究组与对照组,各40例;对照组给予常规头孢噻肟钠治疗,研究组给予头孢米诺钠治疗,比较两组患者的临床治疗效果、细菌清除率和不良反应发生率。结果研究组患者临床治疗总有效率92.5%,显著高于对照组的70.0%,差异有统计学意义(P<0.05);研究组患者治疗后细菌清除率97.5%,显著高于对照组患者的75.0%,差异有统计学意义(P<0.05);研究组不良反应发生率5.0%,低于对照组的17.5%,差异有统计学意义(P<0.05)。结论临床中对于糖尿病合并社区获得性下呼吸道感染患者应用头孢米诺钠治疗效果显著、细菌清除率高、不良反应少,值得临床中应用与推广。
Objective To investigate the application of cefminox sodium in the treatment of community-acquired lower respiratory tract infection with diabetes mellitus, and to provide a reference for the treatment of the disease. Methods Eighty patients with community-acquired lower respiratory tract infection with diabetes were selected from January 2014 to June 2015 in our hospital. The patients were randomly divided into study group and control group, 40 cases in each group. The control group was given routine cefotaxime sodium Treatment, study group were given cefminin sodium treatment, the clinical efficacy of the two groups were compared, bacterial clearance rate and incidence of adverse reactions. Results The total effective rate of clinical treatment in study group was 92.5%, which was significantly higher than that in control group (70.0%, P <0.05). The bacterial clearance rate in study group was 97.5%, which was significantly higher than that in control group The difference was statistically significant (P <0.05). The incidence of adverse reactions in the study group was 5.0%, which was lower than that in the control group (17.5%), the difference was statistically significant (P <0.05). Conclusion Clinical application of cefminox sodium in patients with diabetes mellitus and community-acquired lower respiratory tract infection has significant effect, high bacterial clearance rate and few adverse reactions, which is worthy of clinical application and promotion.