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目的:观察安胃疡胶囊辅助治疗消化性溃疡的临床疗效。方法:选择临床确诊的消化性溃疡480例,随机分为观察组和对照组各240例。对照组采用质子泵抑制药+铋剂+抗生素治疗;观察组在对照组的基础上加用安胃疡胶囊治疗。两组均连续治疗4周。观察两组治疗后临床症状改善情况、内镜下溃疡愈合情况及药物不良反应发生情况。结果:观察组临床症状改善总有效率86.7%,显著高于对照组的66.7%(P<0.05);观察组内镜下溃疡愈合总有效率为80.0%,显著高于对照组的66.7%(P<0.05);两组均未发生严重不良反应。结论:在常规治疗基础上加用安胃疡胶囊,能有效改善消化性溃疡的临床症状,促进溃疡愈合。
Objective: To observe the clinical effect of Anweiyang capsule in the treatment of peptic ulcer. Methods: A total of 480 patients with peptic ulcer were selected and randomly divided into observation group (240 cases) and control group (240 cases). The control group was treated with proton pump inhibitor + bismuth + antibiotics; the observation group was treated with Anweiyang capsule on the basis of the control group. Two groups were treated for 4 weeks. The improvement of clinical symptoms, endoscopic ulcer healing and adverse drug reactions were observed in both groups after treatment. Results: The total effective rate of clinical symptom improvement in observation group was 86.7%, which was significantly higher than that in control group (66.7%, P <0.05). The ulcer healing rate in observation group was 80.0%, which was significantly higher than that in control group (66.7% P <0.05). No serious adverse reactions occurred in both groups. Conclusion: Anweiwei capsule can be used to improve the clinical symptoms of peptic ulcer and promote the healing of ulcer.