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本文首次应用国产卡托普利针剂治疗50例重症CHF,并对其中23例进行用药前、后的血浆肾素系统水平测定,以观察其疗效。结果表明,静注卡托普利可以使心率、平均动脉压轻度下降(P>0.05),迅速缓解症状,使血浆AngⅡ及Aldo显著下降,认为可作为治疗重症CHF时的一线选择药物。
This article for the first time using domestic captopril injection treatment of 50 cases of severe CHF, and of which 23 cases before and after treatment of plasma renin system level to observe its efficacy. The results showed that captopril intravenously decreased heart rate and mean arterial pressure (P> 0.05), relieved the symptoms rapidly, and remarkably decreased plasma AngⅡ and Aldo levels, suggesting that captopril can be used as a first-line drug in the treatment of severe CHF.