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１０例原发性肝癌患者经腹脉动脉门静脉双重插管，同时化疗栓塞，并观察了术前术后肝脏储备功能指标的变化。１０例患者的肝实质栓塞率在８．３６％～４７．８％。其中４例接近或超过４０％，血浆中ｃＡＭＰ基础浓度，术前术后相比无显著变化，Ｐ＞０．０５，经胰高血糖素负荷后，ｃＡＭＰ浓度从术前的２７８．３１降至术后的１４２．３８ｐｍｏｌ／ｍｌ，Ｐ＜０．０５，４例术后ｃＡＭＰ明显低下（小于９０ｐｍｏｌ／ｍｌ）；患者术前肝动脉门静脉血流灌注指数与肝硬化时改变相似，８例中２例肝动脉门静脉血流均增加，３例肝动脉血流增加，门静脉减少，另外３例则相反；３例栓塞率较高。负荷后ｃＡＭＰ低下者出现了一过性黄疸和腹水。结果表明：①双重栓塞可损害一部分肝实质，对肝脏储备功能产生一定影响，但尚在代偿范围之内；②双栓范围较大，ｃＡＭＰ低下时注意保护功能；③双栓后肝血流的变化复杂，应进一步研究必手术操作简便，方法可靠安全。
Ten patients with primary liver cancer were treated with dual portal vein arterial intubation and concurrent chemoembolization. Changes in liver reserve function before and after surgery were observed. The hepatic parenchymal embolism rate in 10 patients ranged from 8.36% to 47.8%. Four of these patients were close to or more than 40%. The plasma cAMP baseline level was not significantly changed before and after surgery. P>0.05. After glucagon loading, the cAMP concentration decreased from 278.31 preoperatively. Postoperative 142.38pmol/ml, P<0.05, postoperative cAMP was significantly lower (less than 90 pmol/ml) in 4 patients; the preoperative hepatic arterial portal vein perfusion index was similar to that in liver cirrhosis, and 8 of 2 cases The hepatic arterial portal vein blood flow increased, 3 cases had hepatic arterial blood flow increased, and the portal vein decreased. The other 3 cases were the opposite; the embolization rate was higher in 3 cases. A person with low cAMP after the load had transient jaundice and ascites. The results showed that: 1 double embolism can damage some of the liver parenchyma, and have a certain impact on the liver reserve function, but it is still within the scope of compensation; 2 a large range of double embolus, attention to protective function when cAMP is low; 3 double hepatic blood flow after suppository The changes are complex and should be further studied to be easy to operate, safe and reliable.