新生儿肺脓疡分为原发性及继发性两大类。前者源于支气管,起源于新生儿呼吸道从鼻咽向下扩展;后者常继发于败血症,是由皮肤、粘膜、脐部残端及鼻咽等原发灶经血行播散至肺、骨、脑及其他内脏,而导致多发性小脓疡,发病率占新生儿住院总数的0.5％,新生儿尸检的5％。一、病因及发病机理 1、新生儿时期由于非特异性及特异性免疫功能均有缺陷,如皮肤、粘膜薄嫩,易于破损;网状内皮系统清除力较低;血液中缺少抗体、补体,且不耐热因子偏低,因而使新生儿白细胞吞噬过程中的调理、趋化及吞噬作用均较差,故细菌侵入早期。白细胞不能发挥有效的吞噬作用,使感 Neonatal lung abscess is divided into two major categories of primary and secondary. The former is derived from the bronchi, originated in the respiratory tract of newborns from the nasopharynx downward expansion; the latter often secondary to sepsis, is by the skin, mucous membranes, umbilical stump and nasopharyngeal and other primary tumor disseminated through the blood to the lungs, bone , Brain and other internal organs, resulting in multiple small abscess, the incidence of neonatal hospitalizations accounted for 0.5% of the total, 5% of neonatal autopsy. First, the etiology and pathogenesis 1, Neonatal non-specific and specific immune function due to defects, such as the skin, mucous membrane thin and tender, easy to damage; reticuloendothelial system clearance is low; lack of blood antibodies and complement, and Low heat-resistant factors, so that the process of neonatal leukocyte phagocytosis, chemotaxis and phagocytosis are poor, so the bacteria invade early. Leukocytes can not play an effective phagocytosis, so flu