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结直肠癌(CRC)是一种常见恶性肿瘤,严重威胁着人类健康。美国癌症统计数据显示2010年新发结直肠癌约14万例,而有5万余例患者死于该病[1]。尽管发达国家发病率及死亡率呈逐年下降的趋势,但结直肠癌依然位列恶性肿瘤的第三位。在我国,由于生活方式的转变及饮食结构的西化,结直肠癌发病率以每年超过4%的速度在递增,远超2%的国际水平,已升至恶性肿瘤的第4位。在初治结直肠癌患者中,I~III期患者约占50%左右。I期结肠癌术后5年生存率85%~95%[2-3],因此对于I期患者术后不推荐使用辅助化疗;III期结
Colorectal cancer (CRC) is a common malignant tumor that is a serious threat to human health. US cancer statistics show about 140,000 new cases of colorectal cancer in 2010, while more than 50,000 patients die of the disease [1]. Despite the declining trend in morbidity and mortality in developed countries, colorectal cancer still ranks third among malignant tumors. In our country, due to the change of life style and the westernization of diet, the incidence of colorectal cancer is increasing at an annual rate of more than 4%, far exceeding the 2% international standard and has risen to No. 4 in malignant tumors. In newly diagnosed patients with colorectal cancer, I ~ III patients account for about 50%. Stage I colon cancer 5-year survival rate of 85% to 95% [2-3], so for I phase of the patient is not recommended adjuvant chemotherapy; stage III