舍格林综合征(Sjogren syndrome,SS),是以口腔干燥和干燥性角膜结膜炎为主要症状,唾液腺和泪腺等外分泌腺受到特异性损害的自身免疫性疾患。据报道,在SS患者的唾液腺导管周围可见T细胞浸润,其中CD4阳性T细胞对发病起重要作用。另有报道,SS患者的唾液腺导管上皮HLA-DR抗原表达异常。该文作者对SS患者唇腺腺泡及导管上皮细胞HLA-DR抗 Sjogren’s syndrome (SS) is an autoimmune disorder characterized by dry mouth and dry keratoconjunctivitis, and exocrine glands such as the salivary gland and lacrimal gland. It is reported that infiltration of T cells is seen around the salivary gland ducts of SS patients, of which CD4-positive T cells play an important role in the pathogenesis. It was also reported that abnormal expression of HLA-DR antigen in salivary gland ductal epithelium of SS patients. The author of SS patients with laryngeal acinar and ductal epithelial cells HLA-DR anti