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尤文氏肉瘤(E S)在外科病理学中是诊断和组织学上存在问题最多的肿瘤之一。自1921年以来,曾提出许多组织来源的理论,以解释这种肿瘤的形态学,甚至某些作者对这一病理学疾病,提出否定的意见.大多数学者认为其组织来自症状出现时骨病变的原发部位。并认为儿童时期的其他小细胞肿癌和来自骨髓或生骨细胞的肿瘤系这一肿瘤的来源.最近,类似尤文氏肉瘤的骨外肿瘤已有所报导。故提出这一肿瘤系来源于新的细胞。ES 的组织学诊断问题,可认为基本上属单一细胞成份,即由小圆形、分化不良的细胞构成。儿童期需与成神经细胞瘤,横纹肌肉瘤,淋巴瘤白血病及水细胞骨肉瘤相鉴别.在成人除了上述肿瘤之外,尚应与转移的小细胞癌,血管肉瘤及间
Ewing’s sarcoma (E S) is one of the most problematic and histologically-prone tumors in surgical pathology. Since 1921, many organizational sources have been proposed to explain the morphology of this tumor, and even some authors have expressed negative opinions on this pathological disease. Most scholars believe that their organization comes from the appearance of bone lesions when symptoms occur. The primary site. It is believed that other small cell tumors in childhood and tumors from bone marrow or osteoblasts are the source of this tumor. Recently, extra-skeletal tumors similar to Ewing’s sarcoma have been reported. Therefore, it is proposed that this tumor is derived from new cells. The histological diagnosis of ES may be considered to consist essentially of a single cell component, ie, a small, poorly differentiated cell. In childhood, it needs to be differentiated from neuroblastoma, rhabdomyosarcoma, lymphoma leukemia, and osteosarcoma of the water cell. In addition to the aforementioned tumors in adults, small cell carcinoma, angiosarcoma, and metastases should be used.