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目的探讨早产儿血清胃泌素(gastrin,GAS)水平与喂养不耐受的相关性因素。方法将临床诊断为喂养不耐受的早产儿(均为32-35周)24例作为观察组,对照组20例为我院产科同期出生的足月儿(均为37-42周)。两组患儿分别在生后24小时内及生后第7天行血清GAS水平的测定,观察两组患儿治疗一周后血清GAS水平的变化。结果观察组在入院时的血清GAS水平较对照组显著减低,治疗7天后两组血清GAS水平无显著差异(P>0.05)。结论早产儿血清GAS水平与喂养不耐受的发生关系密切。
Objective To investigate the relationship between serum gastrin (GAS) levels and feeding intolerance in preterm infants. Methods 24 cases of preterm infants (32-35 weeks old) who were intolerant to feeding were selected as the observation group and 20 cases of full-term infants born in the same period of obstetrics and gynecology (both 37-42 weeks) in the control group. Serum GAS levels were measured within 24 hours after birth and on the 7th day after birth in both groups, and the change of serum GAS level was observed after one week of treatment in both groups. Results The level of serum GAS in the observation group was significantly lower than that in the control group. There was no significant difference in serum GAS levels between the two groups after 7 days of treatment (P> 0.05). Conclusion Serum GAS levels in preterm infants are closely related to the development of feeding intolerance.