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小儿克山病中有相当数量的病例并发有间质性肺炎,这在临床与病理解剖上均有报导。但从克山病并发肺炎的心肺两组织同时分离病毒的报道尚未见到。作者从楚雄地区小儿克山病并发肺炎的5例尸检心肺两组织中,用猴肾传代细胞(MK_2株)进行病毒分离的结果是:其中1例是心肺两组织病毒分离均阳性,另1例是心肌病毒分离阳性,肺组织阴性。还有1例是肺组织病毒分离阳性,心肌阴性,其余两例均阴性,表明病毒在两组织中并非固定同时并存,亦非固定相伴。本次所分离的4株病毒经血清学鉴定均属CoxB_5型病毒,是当时占优势的毒株。
Pediatric Keshan disease in a considerable number of cases complicated by interstitial pneumonia, which has been reported in clinical and pathological anatomy. However, Keshan disease complicated by pneumonia in both heart and lung tissue isolation of the virus has not yet been reported. The results of virus isolation from monkey kidney passage cells (MK_2 strain) in 5 cases of cardiopulmonary and cor pulmonale in 5 cases of pediatric Keshan disease complicated with pneumonia in Chuxiong region were as follows: 1 case was positive separation of cardiopulmonary and 2 viral isolates, and 1 case Is positive myocardial cardiomyopathy, lung tissue negative. Another case of pulmonary virus positive isolation, myocardial negative, the other two were negative, indicating that the virus is not fixed in both organizations coexist, nor accompanied by fixed. The four isolates were serologically identified as CoxB_5 and were the predominant strains at that time.