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目的观察后扩张在老年患者冠状动脉钙化病变经皮冠状动脉介入治疗(percutaneous coronary intervention,PCI)术中应用的疗效和安全性。方法选择PCI血管造影成功的老年钙化血管造影病变患者124例,随机分为后扩张组(62例)和对照组(常规置入组;62例),观察两组患者PCI术中并发症发生率及住院期间及术后1年支架内血栓、再狭窄和主要不良心脏事件(major adverse cardiac events,MACE)发生率。结果后扩张组和常规置入组患者PCI术中并发症发生率两组间比较差异无显著性(6.5%︰4.8%,P>0.05);1年时的随访结果显示,后扩张组的MACE发生率较对照组降低(4.8%︰12.9%,P<0.05);支架内血栓和支架内再狭窄发生率较常规置入组均明显减少(1.6%︰4.8%;4.4%︰14.3%,P<0.05),差异有显著性。结论在老年钙化病变患者PCI术中应用后扩张治疗安全、有效,能够降低支架内血栓、再狭窄和MACE发生率。
Objective To observe the effect and safety of post-dilation in the treatment of coronary artery calcification with percutaneous coronary intervention (PCI) in elderly patients. Methods A total of 124 elderly patients with calcified angiography undergoing PCI angiography were randomly divided into post-dilatation group (n = 62) and control group (n = 62). The incidence of complications And the incidence of stent thrombosis, restenosis and major adverse cardiac events (MACE) during hospitalization and 1 year after surgery. Results There was no significant difference in the incidence of complications after PCI between the two groups (6.5%: 4.8%, P> 0.05). The follow-up results at 1 year showed that the MACE The incidence of in-stent thrombosis and in-stent restenosis were significantly lower than those in the control group (4.8%: 12.9%, P <0.05) <0.05), the difference was significant. Conclusion The application of post-dilatation in the treatment of elderly patients with calcified lesions is safe and effective and can reduce the incidence of thrombosis, restenosis and MACE in the elderly.