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目的分析妊娠期间新发生的系统性红斑狼疮患者临床用药治疗情况,为临床提供用药指导。方法报道1例妊娠合并系统性红斑狼疮的临床用药诊治过程。结果该患者在怀孕期间使用糖皮质激素、羟氯喹及丙种球蛋白控制狼疮活动,病情控制平稳,于38周多时行剖宫产娩出一足月成熟女婴,Wt:2.75kg,Ht:46cm,自然啼哭,响亮,呼吸顺,无气促、发绀,无畸形,轻度黄疸,新生儿狼疮。结论妊娠合并系统性红斑狼疮患者在医生指导下正确使用糖皮质激素、羟氯喹等药物,能获得良好的结局。
Objective To analyze the clinical treatment of newly diagnosed systemic lupus erythematosus during pregnancy and provide guidance for clinical application. Methods One case of clinical diagnosis and treatment of pregnancy complicated with systemic lupus erythematosus was reported. Results During the pregnancy, the patient used glucocorticoid, hydroxychloroquine and gamma globulin to control the activity of lupus, and the disease was controlled smoothly. One full-term mature baby girl was delivered by cesarean section at 38 weeks old. Wt: 2.75kg, Ht: 46cm, natural Crying, loud, breathless, airless, cyanotic, deformity, mild jaundice, neonatal lupus. Conclusion Pregnancy with systemic lupus erythematosus in patients under the guidance of a doctor correct use of glucocorticoids, hydroxychloroquine and other drugs, can get a good outcome.