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目的 :观察降纤酶对急性脑梗死的疗效及对血流变学指标的影响。方法 :采用随机双盲安慰对照法 ,应用降纤酶治疗急性脑梗死 2 4例 (对照 2 4例 )。结果 :治疗组于应用降纤酶后第 5日血纤维蛋白原、红细胞压积、血浆比粘度较治疗前明显下降 ,而对照组仅有轻度下降 ,两组间有显著差异 (P 〈0 .0 5 )。结论 :脑梗死急性期应用降纤酶可以发挥其降纤及降低血液粘滞性作用 ,改善脑缺血状态
Objective: To observe the effect of defibrase on acute cerebral infarction and its effect on hemorheology. Methods: Randomized double-blind comfort control method, the application of defibrase in the treatment of 24 cases of acute cerebral infarction (control 24 cases). Results: In the treatment group, the fibrinogen, hematocrit and plasma viscosities were significantly decreased on the 5th day after the application of defibrase, while the control group only slightly decreased, with significant difference between the two groups (P <0 .0 5). Conclusion: The application of defibrase in the acute stage of cerebral infarction can exert its function of lowering fibrosis and reducing blood viscosity, and improve the state of cerebral ischemia